Downstream Scientist

Publiceringsdatum: 2025-03-18

Skulle du vilja jobba inom naturvetenskap? Nu har du chansen att börja jobba som civilingenjör, bioteknik hos Haeger & Carlsson Executive Search and Interim A. Haeger & Carlsson Executive Search and Interim A söker en medarbetare på heltid som vill arbeta tills vidare. Kan det vara du?

Arbetsplatsen ligger nära tillhands om du är bosatta i Umeå som är tjänsteorten. Haeger & Carlsson Executive Search and Interim A söker efter fler duktiga individer som vill arbeta som civilingenjör, bioteknik. De har just nu ett ledigt jobb som civilingenjör, bioteknik som kan vara av intresse för dig. Låt Haeger & Carlsson Executive Search and Interim A hjälpa dig att uppnå dina karriärmål som civilingenjör, bioteknik! Ansök seast tisdag den tjugonionde april 2025.

Jobbannons

If you are an experienced Downstream Scientist and are looking for a new position at a company with an exciting future ahead this might be something for you

Haeger&Carlsson are recruiting a Downstream Scientist to join Diamyd Medical’s Biologics Manufacturing facility in Umeå.

Diamyd Medical develops precision medicine therapies for Type 1 Diabetes. Diamyd® is an antigen-specific immunotherapy for the preservation of endogenous insulin production. DIAGNODE-3, a confirmatory Phase III trial is actively recruiting patients with recent-onset Type 1 Diabetes in eight European countries and in the US. A biomanufacturing facility is being set up in Umeå for the manufacture of recombinant GAD65, the active ingredient in the antigen-specific immunotherapy Diamyd®.

We are looking for an experienced Downstream scientist with deep subject matter expertise in eucaryotic cell culture to advance the downstream process. The ideal candidate will possess extensive experience with downstream and a strong background in optimizing protein purification. This role involves designing and executing experiments to enhance the biological manufacturing processes. You will be part of the process development department and report to Manufacturing Manager.

Key responsibilities:

• Laboratory work such as development work for the downstream process.
• Documentation, establishment and revision of SOPs, methods etc.
• Compile, check and report results.
• Hold instrument responsibility.
• Participate in deviation investigations.
• Participate in the improvement work within the downstream lab.
• Planning of own work according to given priorities and time frames.

Qualifications:

• PhD or BSc/MSc in Cell Biology, Biotechnology, Biochemical Engineering or a related field.
• Subject matter expertise in purification of proteins. A good track record of different techniques involved in the downstream processing, such as TFF, different chromatographic techniques and nanofiltration.
• Experience with optimization of protein purification.
• Experience in downstream processing is a requirement, and industry experience is a strong plus.
• General laboratory techniques such as: cultivation and analysis (SDS-PAGE, Western blotting, ELISA, HPLC, qPCR, flow cytometry).
• Literature-driven experimental design including preparation of experimental plan and detail procedure, processing of raw data, and summarizing the experiments including conclusion and proposed follow up experiments in the report format.
• Experience working within cGMP guidance and any another applicable regulations is considered a plus.
• Experience with creating Standard Operating Procedures (SOPs) for equipment and processes, as well as Manufacturing Batch Records (MBR) protocols, along with the ability to follow written instructions such as SOPs and MBRs.
• Ability to work independently, set goals, and achieve results.
• Strong analytical and critical thinking skills.
• Strong verbal and written communication skills with high proficiency in spoken and written English.
• Attention to detail, good time management, and self-motivation.